Jul 18, · One major area where acne can cause issues is on the face, specifically around the follicles of facial hair. Although men are more likely to deal with acne and facial hair, women also can be plagued with both facial hair growth and acne formation. Skin Cells and Sebum. We have heard many complaints from patients that facial hair removal treatments, such as threading, plucking and waxing, can lead to acne breakouts afterwards. The most common sort of breakout is little white bumps in the area that the hair was removed. The breakouts usually occur as a result of irritation from the hair removal process.